WebJun 21, 2016 · Phospho-H2AX or γ-H2AX- is a marker of DNA double-stranded breaks and can therefore be used to monitor DNA repair after, for example, irradiation. In addition, positive staining for phospho-H2AX may indicate genomic instability and telomere dysfunction in tumour... WebJul 12, 2024 · Background Replication stress (RS) gives rise to DNA damage that threatens genome stability. RS can originate from different sources that stall replication by diverse …
γH2AX: a sensitive molecular marker of DNA damage and …
WebFind the latest Castile Resources Limited (CST.AX) stock quote, history, news and other vital information to help you with your stock trading and investing. WebJan 5, 2010 · Background Evidence suggests that tumor cells exposed to some DNA damaging agents are more likely to die if they retain microscopically visible γH2AX foci that are known to mark sites of double-strand breaks. This appears to be true even after exposure to the alkylating agent MNNG that does not cause direct double-strand breaks … bitmap marked for reuse can\\u0027t fit new bitmap
Use of the γ-H2AX Assay to Investigate DNA Repair Dynamics
WebAnti-phospho-Histone H2A.X (Ser139) Antibody, clone JBW301 is a highly specific mouse monoclonal antibody, that targets Histone H2A.X & has been tested in western blotting, ICC, ChIP & Immunof. MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents. WebHistone H2AX in HeLa Human Cell Line. Histone H2AX was detected in immersion fixed HeLa human cervical epithelial carcinoma cell line using … WebSpecificity. ab124781 does not work in ICC/IF on PFA fixed cells but does work on methanol fixed cells. The immunogen used for this product shares full homology with other H2A proteins, including H2A1, H2A1B, H2A2A and H2AZ. Cross-reactivity with these proteins has not been confirmed experimentally. data factory concat variables